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What Is Delta-Tocotrienol?

The vitamin E family consists of eight different molecules - four Tocopherols and four Tocotrienols. All are tadpole-shaped with a head and a tail. Tocopherols have straight tails. Tocotrienols have "wig-wag" tails with three unique double bonds that permit its gifted properties. (Tocopherols lack these double bonds.)

Tocopherols and Tocotrienols come in four configurations - alpha, beta, gamma, and delta - determined by the number and location of methyl groups in their heads. Delta-Tocotrienol is the first and smallest of the eight vitamin E molecules made by nature, allowing greatest mobility through membranes providing rapid responses to cell damages, as the best-in-class, fat-soluble antioxidant and anti-inflammatory agent. Smaller is Better.

Tocotrienol

Delta-Tocotrienol is also gifted with cardiovascular and cancer benefits... It inhibits monocyte adherence to arterial endothelium in fatty streak formation - one of the first steps in plaque formation. It improves arterial health by preventing the artery walls from getting too narrow and forming blood clots. It inhibits liver cholesterol biosynthesis and decreases Total and LDL cholesterol and triglycerides. It fights cancer by targeting multiple cell signaling pathways and inhibiting cancer cell growth and metastasis. It induces apoptosis (programmed cell death) in cancer cells selectively and causes tumor regression by inhibiting cellular telomerase and promoting anti-angiogenesis (thereby starving the tumor) in cancer and macular degeneration. It also stimulates cytoprotective autophagy in certain cancers.

What are Tocotrienols? Video

Two notable patents include:

Delta-Tocotrienol received U.S. Patent (#8846653) for the Treatment and Prevention of Pancreatic Cancer (Human)

U.S. Patent #8846653

World I.P. Patent (#WO2009/126866A2) as a Radioprotective Countermeasure Agent.

World I.P. Patent #WO2009126866A2

  • Treating the Effects of Ionizing Radiation & Significantly Enhancing Subject Survivability
  • Selectively Sensitizing Melanoma Cells to Ionizing Radiation
  • Enhancing the Immune System
  • Helping Bone Healing (Bone Marrow)
  • Strengthening Osteoporotic Bone
  • Delaying Onset of Alzheimer's Disease & Other Neurological Disorders
  • Helping Prevent Cataracts
  • Protecting Skin from UV Radiation
  • Improving Skin Elasticity
  • Helping Heal Arthritis

Notable Published Research Articles

Tocotrienol Supplementation Suppressed Bone Resorption and Oxidative Stress in Postmenopausal Osteopenic Women: a 12-week randomized double-blinded placebo-controlled trial. (January 2018)
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Efficacy of Oral Mixed Tocotrienols in Diabetic Peripheral Neuropathy: A Randomized Clinical Trial. (January 2018)
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Supplementation with Tocotrienols from Bixa orellana Improves the in vivo Efficacy of Daptomycin Against Methicillin-Resistant Staphylococcus Aureus (MRSA) in a mouse model of infected wound. (September 2017)
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Tocotrienols for Bone Health: a Translational Approach. (August 2017)
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Biological Properties of Tocotrienols: Evidence in Human Studies (October 2016)
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Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds. (January 2016)
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A Phase I Safety, Pharmacokinetic, and Pharmacodynamic Presurgical Trial of Vitamin E δ-tocotrienol in Patients with Pancreatic Ductal Neoplasia. (November 2015)
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miR-429 Mediates Delta-Tocotrienol-induced Apoptosis in Triple-Negative Breast Cancer Cells by Targeting XIAP. (September 2015)
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A New Formulation of Gamma - Delta Tocotrienol has Superior Bioavailability Compared to Existing Tocotrienol-Rich Fraction in Healthy Human Subjects (September 2015)
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Gamma-Tocotrienol-induced Autophagy in Malignant Mammary Cancer Cells. (November 2013)
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Annatto Tocotrienol Induces a Cytotoxic Effect on Human Prostate Cancer PC3 Cells via the Simultaneous Inhibition of Src and Stat3. (June 2015)
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The Biological Effects of Tocotrienol on Bone: a Review on Evidence from Rodent Models. (April 2015)
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Dose-dependent Modulation of Lipid Parameters, Cytokines and RNA by δ-tocotrienol in Hypercholesterolemic Subjects Restricted to AHA Step-1 Diet (December 2014)
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Bioavailability of Tocotrienols: Evidence in Human Studies (January 2014)
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Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease (January 2014)
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Vitamin E: Tocopherols and Tocotrienols as Potential Radiation Countermeasures (November 2013)
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Vitamin E Tocotrienol Supplementation Improves Lipid Profiles in Chronic Hemodialysis Patients. (September 2013)
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Tocotrienols: inflammation and cancer. (July 2011)
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Tocotrienols, the Vitamin E of the 21st Century: It’s Potential Against Cancer and Other Chronic Diseases (December 2010) 
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Anti-angiogenic function of tocotrienol. (2008)
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Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations (August 2004)
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Disclaimer

We are not making any claims that this product will cure cancer. This website is for informational purposes only. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.